Bryostatin 3

MedChem Express

Bryostatin 3 [143370-84-7]

10

143370-84-7

Research Use Only

C46H64O17

888.99

Bryostatin 3, a macrocyclic lactone, is a protein kinase C activator, with a K i of 2.75 nM. Bryostatin 3 can block 12-O-tetradecanoylphorbol-13-acetate (TPA) inhibition of cell proliferation, yet did not block TPA-enhanced cell-substratum adhesion [1] [2] .

CCC/C=C/C=C/C(O[C@H]1C([C@@](O2)([H])[C@]3([H])O[C@]1(C(C)(/C=C\[C@](C/4)([H])O[C@](CC4=C\C(OC)=O)([H])C[C@@](C(C)([C@@H](OC(C)=O)C[C@@]5([H])C[C@@H](O)CC(OC([C@H](O)C)C3)=O)C)(O5)O)C)O)=CC2=O)=O

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