BSEP

Biorbyt

BSEP

10

ImmunoHistoChemistry

IHC

Research Use Only

Monoclonal

IHC518

Unconjugated

Mouse

IgG1

Bile Salt Export Pump (BSEP) is a member of the ATP-binding cassette (ABC) transporters, and mediates the transport of bile acid, taurocholate, and other cholate conjugates across the hepatocyte canalicular membrane into the canaliculus. BSEP is associated with progressive familial intrahepatic cholestasis type 2 (PFIC2) and benign recurrent intrahepatic cholestasis type 2 (BRIC2). PFIC2 caused by mutations in the BSEP gene increases the risk of hepatocellular carcinoma in early life.

Human

2°C to 8°C

12352203