BSJ-01-175

MedChem Express

BSJ-01-175 [2227392-55-2]

62

2227392-55-2

Research Use Only

99.45

C30H33ClN6O2

545.08

BSJ-01-175 is a potent and selective CDK12/13 covalent inhibitor. BSJ-01-175 demonstrates exquisite selectivity, potent inhibition of RNA polymerase II phosphorylation, and downregulation of CDK12-targeted genes in cancer cells [1] .

ClC1=CN=C(N[C@H]2C[C@@H](CCC2)OC3=CC=C(C=C3)NC(/C=C/CN(C)C)=O)N=C1C4=CNC5=CC=CC=C45

-20°C,2°C to 8°C

12352200