BTSA1 [314761-14-3]

MedChem Express

BTSA1 [314761-14-3]

9

314761-14-3

Research Use Only

99.77

C21H14N6OS2

430.51

BTSA1 is a potent, high affinity and orally active BAX activator with an IC50 of 250 nM and an EC50 of 144 nM. BTSA1 binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis[1].

O=C(N(C1=NC(C2=CC=CC=C2)=CS1)N=C/3C4=CC=CC=C4)C3=N\NC5=NC=CS5

-20°C,2°C to 8°C

12352200