BTX161 [2052301-24-1]

MedChem Express

BTX161 [2052301-24-1]

10

2052301-24-1

Research Use Only

99.20

C15H16N2O3

272.304

BTX161, a thalidomide analog, is an effective CKIalpha degrader. BTX161 mediates human AML cell CKIalpha degradation more effectively than lenalidomide and activates the DNA damage response (DDR) and p53, while stabilizing p53 antagonist MDM2.

O=C([C@@H](N(CC1=C2C=CC=C1C)C2=O)CCC3)NC3=O

-20°C,2°C to 8°C

12352200