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BU224 (hydrochloride)

HY-101170
MedChem Express
CAS Number205437-64-5
DownloadMSDS
Product group Chemicals
Estimated Purity96.35
Molecular Weight233.70
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Overview

  • Supplier
    MedChem Express
  • Product Name
    BU224 (hydrochloride) [205437-64-5]
  • Delivery Days Customer
    10
  • CAS Number
    205437-64-5
  • Certification
    Research Use Only
  • Estimated Purity
    96.35
  • Molecular Formula
    C12H12ClN3
  • Molecular Weight
    233.70
  • Scientific Description
    BU224 hydrochloride is a selective and high affinity imidazoline I 2 receptor ligand, with a K i of 2.1 nM. BU224 hydrochloride is sometimes used as an I 2 receptor antagonist. BU224 hydrochloride exerts neuroprotective effects, with anti-inflammatory and anti-apoptotic properties. BU224 hydrochloride improves memory in 5XFAD mice, enlarging dendritic spines and reducing Abeta-induced changes in NMDARs. BU224 hydrochloride can be used for Alzheimers disease research [1] [2] [3] .
  • SMILES
    C1(C2=NCCN2)=NC3=CC=CC=C3C=C1.Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200