BuChE-IN-TM-10 [2313524-95-5]

MedChem Express

BuChE-IN-TM-10 [2313524-95-5]

10

2313524-95-5

Research Use Only

C32H38N2O3

498.66

BuChE-IN-TM-10 (TM-10) is a potent butyrylcholinesterase (BuChE) inhibitor, with an IC50 of 8.9 nM. BuChE inhibitor 1 inhibits and disaggregates self-induced Abeta aggregation, exhibiting potent antioxidant activity and good blood-brain barrier (BBB) penetration. Has potential to treat Alzheimers disease[1].

O=C(N1CC2=C(C=CC=C2)CC1)/C=C/C3=CC=C(OCCCCN(CC4=CC=CC=C4)CC)C(OC)=C3

12352200