Butein [487-52-5]
HY-16558
Overview
- SupplierMedChem Express
- Product NameButein [487-52-5]
- Delivery Days Customer10
- CAS Number487-52-5
- Estimated Purity98.01%
- Molecular FormulaC15H12O5
- Molecular Weight272.25
- Scientific DescriptionButein is a cAMP-specific PDE inhibitor with an IC50 of 10.4 microM for PDE4. Butein is a specific protein tyrosine kinase inhibitor with IC50s of 16 and 65 microM for EGFR and p60c-src in HepG2 cells. Butein sensitizes HeLa cells to Cisplatin through AKT and ERK/p38 MAPK pathways by targeting FoxO3a. Butein is a SIRT1 activator (STAC).
- SMILESOC1=CC=C(C(/C=C/C2=CC(O)=C(O)C=C2)=O)C(O)=C1
- Storage Instruction2°C to 8°C,-20°C,-80°C
- UNSPSC12352200