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Butein (Standard)

Research Use Only
HY-16558R
MedChem Express
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Butein (Standard) [487-52-5]
  • Delivery Days Customer
    999
  • CAS Number
    487-52-5
  • Certification
    Research Use Only
  • Molecular Formula
    C15H12O5
  • Molecular Weight
    272.25
  • Scientific Description
    Butein (Standard) is the analytical standard of Butein. This product is intended for research and analytical applications. Butein is a cAMP-specific PDE inhibitor with an IC50 of 10.4 microM for PDE4[1]. Butein is a specific protein tyrosine kinase inhibitor with IC50s of 16 and 65 microM for EGFR and p60c-src in HepG2 cells[2]. Butein sensitizes HeLa cells to Cisplatin through AKT and ERK/p38 MAPK pathways by targeting FoxO3a[3]. Butein is a SIRT1 activator (STAC).
  • SMILES
    OC1=CC=C(C(/C=C/C2=CC(O)=C(O)C=C2)=O)C(O)=C1
  • UNSPSC
    12352200