Butein (Standard)

MedChem Express

Butein (Standard) [487-52-5]

9

Research Use Only

Butein (Standard) is the analytical standard of Butein. This product is intended for research and analytical applications. Butein is a cAMP-specific PDE inhibitor with an IC50 of 10.4 microM for PDE4 [1] . Butein is a specific protein tyrosine kinase inhibitor with IC50s of 16 and 65 microM for EGFR and p60c-src in HepG2 cells [2] . Butein sensitizes HeLa cells to Cisplatin through AKT and ERK/p38 MAPK pathways by targeting FoxO3a [3] . Butein is a SIRT1 activator (STAC).

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