BVT 2733 [376640-41-4]

MedChem Express

BVT 2733 [376640-41-4]

5

376640-41-4

Research Use Only

99.72

C17H21ClN4O3S2

428.96

BVT 2733 is a potent, selective, and orally active non-steroidal 11beta-hydroxydehydrogenase 1 (11beta-HSD1) inhibitor. BVT 2733 is potently against the mouse enzyme (IC50=96 nM) over the human enzyme (IC50=3341 nM). BVT 2733 has the potential for the study of arthritis and obesity related disease[1].

ClC1=C(C)C(S(NC2=NC(CC(N3CCN(C)CC3)=O)=CS2)(=O)=O)=CC=C1

-20°C,2°C to 8°C

12352200