BX-912

MedChem Express

BX-912 [702674-56-4]

10

702674-56-4

Research Use Only

99.13

C20H23BrN8O

471.35

BX-912 is a direct, selective, and ATP-competitive PDK1 inhibitor ( IC 50 =26 nM). BX-912 blocks PDK1/Akt signaling in tumor cells and inhibits the anchorage-dependent growth of a variety of tumor cell lines in culture or induces apoptosis [1] .

BrC1=C(NCCC2=CNC=N2)N=C(NC3=CC(NC(N4CCCC4)=O)=CC=C3)N=C1

-20°C,2°C to 8°C

12352200