BX471

MedChem Express

BX471 [217645-70-0]

10

217645-70-0

Research Use Only

99.94

C21H24ClFN4O3

434.89

BX471 (ZK-811752) is an orally active, potent and selective non-peptide CCR1 antagonist with a K i of 1 nM, and exhibits 250-fold selectivity for CCR1 over CCR2, CCR5 and CXCR4.

O=C(N)NC1=CC(Cl)=CC=C1OCC(N2[C@H](C)CN(CC3=CC=C(F)C=C3)CC2)=O

-20°C,2°C to 8°C

12352200