C-021 (dihydrochloride) (Standard) [1784252-84-1]

MedChem Express

C-021 (dihydrochloride) (Standard) [1784252-84-1]

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Research Use Only

C-021 (dihydrochloride) (Standard) is the analytical standard of C-021 (dihydrochloride). This product is intended for research and analytical applications. C-021 dihydrochloride is a potent CC chemokine receptor-4 (CCR4) antagonist. C-021 dihydrochloride potently inhibits functional chemotaxis in human and mouse with IC50s of 140 nM and 39 nM, respectively. C-021 dihydrochloride effectively prevents human CCL22-derived [35S]GTPgammaS from binding to the receptor with an IC50 of 18 nM[1].

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