c-ABL-IN-2 [2574593-54-5]
HY-146527
CAS Number2574593-54-5
Product group Chemicals
Molecular Weight344.41
Overview
- SupplierMedChem Express
- Product Namec-ABL-IN-2 [2574593-54-5]
- Delivery Days Customer10
- CAS Number2574593-54-5
- CertificationResearch Use Only
- Molecular FormulaC21H20N4O
- Molecular Weight344.41
- Scientific Descriptionc-ABL-IN-2 is a potent inhibitor of c-Abl. Activation of c-Abl has been implicated in various diseases, notably cancer. c-ABL-IN-2 has the potential for the research of neurodegenerative diseases (amyotrophic lateral sclerosis (ALS) and Parkinsons disease (PD) and cancer (extracted from patent WO2020260871A1, compound 25)[1]. c-ABL-IN-2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
- SMILESO=C(NC1=CN(C(C)C)C=N1)C2=CC=C(C)C(C#CC3=CC=CN=C3)=C2
- UNSPSC12131703