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c-ABL-IN-2 [2574593-54-5]

HY-146527
MedChem Express
CAS Number2574593-54-5
Product group Chemicals
Molecular Weight344.41
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Overview

  • Supplier
    MedChem Express
  • Product Name
    c-ABL-IN-2 [2574593-54-5]
  • Delivery Days Customer
    10
  • CAS Number
    2574593-54-5
  • Certification
    Research Use Only
  • Molecular Formula
    C21H20N4O
  • Molecular Weight
    344.41
  • Scientific Description
    c-ABL-IN-2 is a potent inhibitor of c-Abl. Activation of c-Abl has been implicated in various diseases, notably cancer. c-ABL-IN-2 has the potential for the research of neurodegenerative diseases (amyotrophic lateral sclerosis (ALS) and Parkinsons disease (PD) and cancer (extracted from patent WO2020260871A1, compound 25)[1]. c-ABL-IN-2 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
  • SMILES
    O=C(NC1=CN(C(C)C)C=N1)C2=CC=C(C)C(C#CC3=CC=CN=C3)=C2
  • UNSPSC
    12131703