c-Met-IN-18

MedChem Express

c-Met-IN-18 [3034863-56-1]

14

Research Use Only

C21H15FN4O2

374.37

c-Met-IN-18 is ATP competitive type-III c-MET inhibitor of WT and D1228V mutant c-MET. c-Met-IN-18 has inhibitory for WT/D1228V with an IC50 value of 0.013/0.20e.c-Met-IN-18 can be used for the research of c-MET driven cancers[1]. c-Met-IN-18 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

O=C1NC(C(C2=CC(F)=CC3=C2NN=C3C#C)=CN1[C@H](C4=CC=CC=C4)C)=O

12131703