c-Met/MEK1/Flt-3-IN-1

MedChem Express

c-Met/MEK1/Flt-3-IN-1

10

Research Use Only

C39H37FN6O5

688.75

Antiproliferative against-3 (comp 33) shows a prominent activity against Hela (IC50 = 0.21 microM), A549 (IC50 = 0.39 microM), and MCF-7 (IC50 = 0.33 microM), respectively. Antiproliferative against-3 (comp 33) also dose dependently induces apoptosis by arresting A549 cells at G1 phase[1].

COC1=C(C=C2N=CC=C(C2=C1)OC3=CC=C(C=C3)NC(C4=CN(C5=C(C4=O)C=CC=N5)C6=CC=C(C=C6)F)=O)OCCCN7CCN(CC7)C

12352200