c-Myc antibody
GTX103436
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetMYC
Overview
- SupplierGeneTex
- Product Namec-Myc antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.29 mg/ml
- ConjugateUnconjugated
- Gene ID4609
- Target nameMYC
- Target descriptionMYC proto-oncogene, bHLH transcription factor
- Target synonymsMRTL, MYCC, bHLHe39, c-Myc, myc proto-oncogene protein, avian myelocytomatosis viral oncogene homolog, class E basic helix-loop-helix protein 39, myc-related translation/localization regulatory factor, proto-oncogene c-Myc, transcription factor p64, v-myc avian myelocytomatosis viral oncogene homolog, v-myc myelocytomatosis viral oncogene homolog
- HostRabbit
- IsotypeIgG
- Protein IDP01106
- Protein NameMyc proto-oncogene protein
- Scientific DescriptionThe protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitts lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Thiamet G as a Potential Treatment for Polycystic Kidney Disease.Read more
- Coating-Free Culture Medium for Establishing and Maintaining Human Induced Pluripotent Stem Cells.Read more
- Telomere Attrition With Concomitant hTERT Overexpression Involved in the Progression of Gastric Cancer May Have Prognostic and Clinical Implications in High-Risk Population Group From North India.Read more
- PRMT1 Confers Resistance to Olaparib via Modulating MYC Signaling in Triple-Negative Breast Cancer. Hsu WJ et al., 2021 Oct 8, J Pers MedRead more
- Calcitriol Suppresses Warburg Effect and Cell Growth in Human Colorectal Cancer Cells. Huang CY et al., 2021 Sep 14, Life (Basel)Read more
- Targeting KDM4B that coactivates c-Myc-regulated metabolism to suppress tumor growth in castration-resistant prostate cancer. Wu MJ et al., 2021, TheranosticsRead more
- Downregulation of Light-Harvesting Complex II Induces ROS-Mediated Defense Against Turnip Mosaic Virus Infection in Nicotiana benthamiana. Qiu S et al., 2021, Front MicrobiolRead more
- A regulatory loop among CD276, miR-29c-3p, and Myc exists in cancer cells against natural killer cell cytotoxicity. Lee CC et al., 2021 Jul 15, Life SciRead more
- USP16 regulates castration-resistant prostate cancer cell proliferation by deubiquitinating and stablizing c-Myc. Ge J et al., 2021 Feb 5, J Exp Clin Cancer ResRead more
- Purified Bighead protein efficiently promotes head development in the South African clawed frog, Xenopus laevis. Colozza G, 2021 Jan 5, MicroPubl BiolRead more
Datasheet
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