ProductsBack/c-Rel antibody [N1N3]

c-Rel antibody [N1N3]

Name: c-Rel antibody [N1N3]
SKU: GTX113264_G10
Availability: BackOrder

GTX113264

ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHuman

TargetREL

Overview

Supplier
GeneTex
Product Name
c-Rel antibody [N1N3]
Delivery Days Customer
9
Application Supplier Note
IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID5966
Target name
REL
Target description
REL proto-oncogene, NF-kB subunit
Target synonyms
C-Rel; HIVEN86A; oncogene REL, avian reticuloendotheliosis; proto-oncogene c-Rel; v-rel avian reticuloendotheliosis viral oncogene homolog
Host
Rabbit
Isotype
IgG
Protein IDQ04864
Protein Name
Proto-oncogene c-Rel
Scientific Description
The REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the Rel domain, which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein, 2007 [PubMed 18037997]).[supplied by OMIM]
Reactivity
Human
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Phosphorylation of NF-kappaBp65 drives inflammation-mediated hepatocellular carcinogenesis and is a novel therapeutic target. Xu X et al., 2021 Aug 11, J Exp Clin Cancer Res
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Identification of a Selective RelA Inhibitor Based on DSE-FRET Screening Methods. Shiroma Y et al., 2020 Nov 30, Int J Mol Sci
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