c-Rel antibody [N1N3]
GTX113264
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetREL
Overview
- SupplierGeneTex
- Product Namec-Rel antibody [N1N3]
- Delivery Days Customer9
- ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID5966
- Target nameREL
- Target descriptionREL proto-oncogene, NF-kB subunit
- Target synonymsC-Rel; HIVEN86A; oncogene REL, avian reticuloendotheliosis; proto-oncogene c-Rel; v-rel avian reticuloendotheliosis viral oncogene homolog
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThe REL gene encodes c-Rel, a transcription factor that is a member of the Rel/NFKB family, which also includes RELA (MIM 164014), RELB (604758), NFKB1 (MIM 164011), and NFKB2 (MIM 164012). These proteins are related through a highly conserved N-terminal region termed the Rel domain, which is responsible for DNA binding, dimerization, nuclear localization, and binding to the NFKB inhibitor (MIM 164008) (Belguise and Sonenshein, 2007 [PubMed 18037997]).[supplied by OMIM]
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203
References
- Phosphorylation of NF-kappaBp65 drives inflammation-mediated hepatocellular carcinogenesis and is a novel therapeutic target. Xu X et al., 2021 Aug 11, J Exp Clin Cancer ResRead more
- Identification of a Selective RelA Inhibitor Based on DSE-FRET Screening Methods. Shiroma Y et al., 2020 Nov 30, Int J Mol SciRead more