C14orf169 / NO66 antibody [C2C3], C-term

GeneTex

C14orf169 / NO66 antibody [C2C3], C-term

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

RIOX1

ribosomal oxygenase 1

60S ribosomal protein L8 histidine hydroxylase; bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; C14orf169; histone lysine demethylase NO66; hsNO66; JMJD9; lysine-specific demethylase NO66; MAPJD; MYC-associated protein with JmjC domain; NO66; nucleolar protein 66; ribosomal oxygenase 1; ribosomal oxygenase NO66; ROX; up-regulated in lung cancer 2; URLC2

Rabbit

IgG

Ribosomal oxygenase 1

Histone demethylase that specifically demethylates Lys-4 (H3K4me) and Lys-36 (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 Lys-4 (H3K4me3) and monomethylated H3 Lys-4 (H3K4me1) residues, while it has weaker activity for dimethylated H3 Lys-36 (H3K36me2). Acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation (By similarity). May also play a role in ribosome biogenesis and in the replication or remodeling of certain heterochromatic region.

Human

-20°C or -80°C,2°C to 8°C

12352203