C14orf169 / NO66 antibody [C2C3], C-term
GTX119355
ApplicationsWestern Blot
Product group Antibodies
TargetRIOX1
Overview
- SupplierGeneTex
- Product NameC14orf169 / NO66 antibody [C2C3], C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID79697
- Target nameRIOX1
- Target descriptionribosomal oxygenase 1
- Target synonymsC14orf169, JMJD9, MAPJD, NO66, ROX, URLC2, hsNO66, ribosomal oxygenase 1, 60S ribosomal protein L8 histidine hydroxylase, MYC-associated protein with JmjC domain, bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66, histone lysine demethylase NO66, lysine-specific demethylase NO66, nucleolar protein 66, ribosomal oxygenase NO66, up-regulated in lung cancer 2
- HostRabbit
- IsotypeIgG
- Protein IDQ9H6W3
- Protein NameRibosomal oxygenase 1
- Scientific DescriptionHistone demethylase that specifically demethylates Lys-4 (H3K4me) and Lys-36 (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 Lys-4 (H3K4me3) and monomethylated H3 Lys-4 (H3K4me1) residues, while it has weaker activity for dimethylated H3 Lys-36 (H3K36me2). Acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation (By similarity). May also play a role in ribosome biogenesis and in the replication or remodeling of certain heterochromatic region.
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203




