C3 antibody
GTX11887
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
Product group Antibodies
ReactivityMouse
TargetC3
Overview
- SupplierGeneTex
- Product NameC3 antibody
- Delivery Days Customer9
- Application Supplier NoteFor IHC-Fr: Use at an assay dependent dilution. For WB: Use at an assay dependent dilution. Optimal dilutions/concentrations should be determined by the end user.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.1 mg/ml
- ConjugateUnconjugated
- Gene ID12266
- Target nameC3
- Target descriptioncomplement component 3
- Target synonymsacylation stimulating protein; AI255234; ASP; complement C3; complement component 3d; complement factor 3; HSE-MSF; Plp
- HostRabbit
- IsotypeIgG
- Protein IDP01027
- Protein NameComplement C3
- Scientific DescriptionThis gene encodes complement protein C3 which plays a central role in the classical, alternative and lectin activation pathways of the complement system. The encoded preproprotein undergoes a multi-step processing to generate various functional peptides. Mice deficient in the encoded protein fail to clear bacteria from the blood stream upon infection, display diminished airway hyperresponsiveness and lung eosinophilia upon allergen-induced pulmonary allergy, and develop severe lung injury after deposition of IgG immune complexes. Deficiency of the homolog of the encoded protein in humans was found to be associated with increased susceptibility to infections, age-related macular degeneration, and atypical hemolytic uremic syndrome. [provided by RefSeq, Mar 2015]
- ReactivityMouse
- Storage Instruction2°C to 8°C
- UNSPSC12352203