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ICC/IF analysis of PC-12 cells using GTX02874 C6ORF150 antibody. Orange : Primary antibody Blue : DAPI Dilution : 1:50
ICC/IF analysis of PC-12 cells using GTX02874 C6ORF150 antibody. Orange : Primary antibody Blue : DAPI Dilution : 1:50
ICC/IF analysis of PC-12 cells using GTX02874 C6ORF150 antibody. Orange : Primary antibody Blue : DAPI Dilution : 1:50

C6ORF150 antibody

GTX02874
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
TargetCGAS
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Overview

  • Supplier
    GeneTex
  • Product Name
    C6ORF150 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500 - 1:2000. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Unconjugated
  • Gene ID115004
  • Target name
    CGAS
  • Target description
    cyclic GMP-AMP synthase
  • Target synonyms
    2'3'-cGAMP synthase; C6orf150; cGAMP synthase; cyclic GMP-AMP synthase; h-cGAS; Mab-21 domain containing 1; mab-21 domain-containing protein 1; MB21D1; protein MB21D1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ8N884
  • Protein Name
    Cyclic GMP-AMP synthase
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Activating cGAS-STING axis contributes to neuroinflammation in CVST mouse model and induces inflammasome activation and microglia pyroptosis. Ding R et al., 2022 Jun 10, J Neuroinflammation
    Read more
  • Mitochondrial damage and activation of the cytosolic DNA sensor cGAS-STING pathway lead to cardiac pyroptosis and hypertrophy in diabetic cardiomyopathy mice. Yan M et al., 2022 May 11, Cell Death Discov
    Read more

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Figure 2. IF analysis of CGAS using anti-CGAS antibody (A31676-1). CGAS was detected in immunocytochemical section of CACO-2 cells. Enzyme antigen retrieval was performed using IHC enzyme antigen retrieval reagent (AR0022) for 15 mins. The cells were blocked with 10% goat serum. And then incubated with 5microg/mL rabbit anti-CGAS Antibody (A31676-1) overnight at 4°C. DyLight®488 Conjugated Goat Anti-Rabbit IgG (BA1127) was used as secondary antibody at 1:100 dilution and incubated for 30 minutes at 37°C. The section was counterstained with DAPI. Visualize using a fluorescence microscope and filter sets appropriate for the label used.
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