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Western Blot analysis of Lovo cell using CAB39 Polyclonal Antibody at dilution of 1:200
Western Blot analysis of Lovo cell using CAB39 Polyclonal Antibody at dilution of 1:200
Western Blot analysis of Lovo cell using CAB39 Polyclonal Antibody at dilution of 1:200

CAB39 Polyclonal Antibody

E-AB-16615
Elabscience
Product group Antibodies
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More than 130 suppliers
ISO certified
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Overview

  • Supplier
    Elabscience
  • Product Name
    CAB39 Polyclonal Antibody
  • Delivery Days Customer
    12
  • Applications Supplier
    ELISA WB IHC
  • Certification
    Research Use Only
  • Concentration
    0.7mg/ml
  • Scientific Description
    Peutz-Jeghers Syndrome (PJS) is a rare hereditary disease characterized by melanocytic macules of the lips, gastrointestinal hamartomatous polyps and an increased risk for many classes of cancer. The serine/threonine kinase LKB1 (also designated STK11) has been identified as the gene mutated in PJS. LKB1 activity increases upon the binding of a regulatory complex consisting of the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase and the calcium binding protein 39 (MO25 alpha). STRAD and MO25 determine the subcellular localization of LKB1 by initiating its translocation from the nucleus to the cytoplasm, thus regulating the tumor suppressor activity of LKB1. The LKB1/STRAD/MO25 complex acts as an AMP-activated protein kinase kinase (AMPKK).
  • UNSPSC
    12352203