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Cabotegravir

HY-15592
MedChem Express
CAS Number1051375-10-0
Product group Chemicals
Estimated Purity99.91
Molecular Weight405.35
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Cabotegravir [1051375-10-0]
  • Delivery Days Customer
    10
  • CAS Number
    1051375-10-0
  • Certification
    Research Use Only
  • Estimated Purity
    99.91
  • Molecular Formula
    C19H17F2N3O5
  • Molecular Weight
    405.35
  • Scientific Description
    Cabotegravir (GSK-1265744) is a orally active and long-acting HIV integrase strand transfer inhibitor and organic anion transporter 1/3 ( OAT1 / OAT3 ) inhibitor with IC 50 values of 2.5 nM, 0.41 microM and 0.81 microM for HIV ADA , OAT3 and OAT1, respectively. Cabotegravir is primarily metabolized by uridine diphosphate glucuronosyltransferase (UGT) 1A1, with low potential to interact with other antiretroviral agents (ARVs). Cabotegravir can be used to research AIDS [1] [2] .
  • SMILES
    FC1=C(CNC(C2=CN3C(C(N([C@@H](C)CO4)[C@@]4([H])C3)=O)=C(O)C2=O)=O)C=CC(F)=C1
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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