WB analysis of human fetal liver tissue using GTX46252 CAml.G antibody at 0.2-1microg/ml.
WB analysis of human fetal liver tissue using GTX46252 CAml.G antibody at 0.2-1microg/ml.
CAMLG antibody, N-term
GTX46252
Overview
- SupplierGeneTex
- Product NameCAMLG antibody, N-term
- Delivery Days Customer9
- Application Supplier NoteWB: 0.2-2.5 ug/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.5-1 mg/ml
- ConjugateUnconjugated
- Gene ID819
- Target nameCAMLG
- Target descriptioncalcium modulating ligand
- Target synonymscalcium signal-modulating cyclophilin ligand; calcium-modulating cyclophilin ligand; CAML; cyclophilin B-binding protein; GET2; guided entry of tail-anchored proteins factor CAMLG
- HostRabbit
- IsotypeIgG
- Protein IDP49069
- Protein NameCalcium signal-modulating cyclophilin ligand
- Scientific DescriptionThe immunosuppressant drug cyclosporin A blocks a calcium-dependent signal from the T-cell receptor (TCR) that normally leads to T-cell activation. When bound to cyclophilin B, cyclosporin A binds and inactivates the key signaling intermediate calcineurin. The protein encoded by this gene functions similarly to cyclosporin A, binding to cyclophilin B and acting downstream of the TCR and upstream of calcineurin by causing an influx of calcium. This integral membrane protein appears to be a new participant in the calcium signal transduction pathway, implicating cyclophilin B in calcium signaling, even in the absence of cyclosporin. [provided by RefSeq, Jul 2008]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203