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CAN508 [140651-18-9]

CAN508 [140651-18-9]

T8796
TargetMol Chemicals
CAS Number140651-18-9
DownloadMSDS
Product group Chemicals
Molecular Weight218.22
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    CAN508 [140651-18-9]
  • Delivery Days Customer
    4
  • CAS Number
    140651-18-9
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    CAN508
  • Molecular Formula
    C9H10N6O
  • Molecular Weight
    218.22
  • Scientific Description
    CAN508 is a potent ATP-competitive CDK9/cyclin T1 inhibitor with an IC50 of 0.35 microM. It also competitively inhibits Cdk2-cyclin E with respect to ATP, with Ki and IC50 values of 13.3 microM and 20 microM, respectively. CAN508 exhibits a 38-fold selectivity for CDK9/cyclin T over other CDK/cyclin complexes. [Antitumor activity.]
  • Shelf life instruction
    3 years
  • SMILES
    Nc1n[nH]c(N)c1\N=N\c1ccc(O)cc1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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