Western Blot Positive WB detected in: Hela whole cell lysate, Jurkat whole cell lysate, 293T whole cell lysate, HepG2 whole cell lysate, MCF-7 whole cell lysate All lanes: CAND1 antibody at 4.9microg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 137, 118, 46 kDa Observed band size: 137 kDa

CAND1 Antibody

CSB-PA774815LA01HU

ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry

Product group Antibodies

TargetCAND1

Overview

Supplier
Cusabio
Product Name
CAND1 Antibody
Delivery Days Customer
20
Applications
ImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID55832
Target name
CAND1
Target description
cullin associated and neddylation dissociated 1
Target synonyms
cullin-associated NEDD8-dissociated protein 1; p120 CAND1; TBP-interacting protein of 120 kDa A; TIP120; TIP120A
Host
Rabbit
Isotype
IgG
Protein IDQ86VP6
Protein Name
Cullin-associated NEDD8-dissociated protein 1
Scientific Description
Key assembly factor of SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complexes that promotes the exchange of the substrate-recognition F-box subunit in SCF complexes, thereby playing a key role in the cellular repertoire of SCF complexes. Acts as a F-box protein exchange factor. The exchange activity of CAND1 is coupled with cycles of neddylation conjugation: in the deneddylated state, cullin-binding CAND1 binds CUL1-RBX1, increasing dissociation of the SCF complex and promoting exchange of the F-box protein. Probably plays a similar role in other cullin-RING E3 ubiquitin ligase complexes.
Storage Instruction
-20°C or -80°C
UNSPSC
12352203

CAND1 Antibody

Large volume orders?

Overview

Related products