Canertinib (dihydrochloride)

MedChem Express

Canertinib (dihydrochloride) [289499-45-2]

10

289499-45-2

Research Use Only

99.68

C24H27Cl3FN5O3

558.86

Canertinib dihydrochloride (CI-1033 dihydrochloride) is a potent and irreversible EGFR inhibitor; inhibits cellular EGFR and ErbB2 autophosphorylation with IC 50 s of 7.4 and 9 nM. Canertinib dihydrochloride is active against vaccinia virus respiratory infection in mice [1] [2] [3] [4] .

C=CC(NC1=CC2=C(N=CN=C2C=C1OCCCN3CCOCC3)NC4=CC=C(C(Cl)=C4)F)=O.[H]Cl.[H]Cl

2°C to 8°C

12352200