Canine CD46 Protein (CD4-DM146)

KACTUS

Canine CD46 Protein (CD4-DM146)

9

Research Use Only

>95%

CD46 was discovered in 1986 during a search for novel C3b-binding proteins. CD46 is expressed ubiquitously and functions as a co-factor in the factor I-mediated proteolytic cleavage of C3b and C4b. Its vital role in preventing complement deposition on host tissue is underpinned by the fact that deficiency of CD46 is a predisposing factor for numerous disease conditions arising from complement-mediated self-attack.

-20°C or -80°C,-80°C

12352202