Canine IL10 ELISA Kit
ARG82642
Product group Assays
Overview
- SupplierArigo Biolaboratories
- Product NameCanine IL10 ELISA Kit
- Delivery Days Customer23
- ApplicationsELISA
- Assay PrecisionIntra-Assay CV: 5%Inter-Assay CV: 8%
- Assay Sensitivity13 pg/ml
- Assay SpecificityThe following recombinant canine proteins were tested and exhibited no cross-reactivity or interference: Adiponectin, ApoAI, BMP1, BMP2, BMP3, BMP4, BMP5, BMP7, CCL2, CCL4, CCL5, CRP, HGF, HSP27, IL1 beta, IL1RA, IL1 alpha, IL1 RI, IL2, IL4, IL5, IL6, IL6
- Assay Time~ 3.5 hours
- CertificationResearch Use Only
- Scientific DescriptionThe protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, May 2011]
- Storage Instruction2°C to 8°C
- UNSPSC41116133