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Canine IL10 ELISA Kit

Research Use Only
ARG82642
Arigo Biolaboratories
Product group Assays
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    Canine IL10 ELISA Kit
  • Delivery Days Customer
    23
  • Applications
    ELISA
  • Assay Precision
    Intra-Assay CV: 5%Inter-Assay CV: 8%
  • Assay Sensitivity
    13 pg/ml
  • Assay Specificity
    The following recombinant canine proteins were tested and exhibited no cross-reactivity or interference: Adiponectin, ApoAI, BMP1, BMP2, BMP3, BMP4, BMP5, BMP7, CCL2, CCL4, CCL5, CRP, HGF, HSP27, IL1 beta, IL1RA, IL1 alpha, IL1 RI, IL2, IL4, IL5, IL6, IL6
  • Assay Time
    ~ 3.5 hours
  • Certification
    Research Use Only
  • Scientific Description
    The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. [provided by RefSeq, May 2011]
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    41116133