Canine IL4 ELISA Kit

Arigo Biolaboratories

Canine IL4 ELISA Kit

23

ELISA

Intra-Assay CV: 6%Inter-Assay CV: 9%

15 pg/ml

The following recombinant canine proteins were tested and exhibited no cross-reactivity or interference: BMP1, BMP2, BMP4, HGF, IL1 beta, IL1RA, IL2, IL5, IL6, IL8, IL10, IL12, IL13, IL15, IFN gamma, MMP2, TGF beta 1, TGF beta 2, TGF beta 3, TLR1, TLR2, T

~ 3 hours

Research Use Only

The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

2°C to 8°C

41116133