Cannflavin A [76735-57-4]

MedChem Express

Cannflavin A [76735-57-4]

14

76735-57-4

Research Use Only

99.20

C26H28O6

436.50

Cannflavin A can be isolated from Cannabis sativa L.. Cannflavin A has anti-cancer, neuroprotective and anti-inflammatory activity. Cannflavin A inhibits Abeta1-42 aggregation. Cannflavin A also inhibits kynurenine-3-monooxygenase (KMO) (IC50 = 29.4 microM). Cannflavin A activates apoptosis via caspase-3 cleavage. Cannflavin A exerts anti-inflammatory effects by inhibiting pro-inflammatory enzymes, including prostaglandin E2 and cytochrome c oxidases I and II in PC12 cell line[1][2][3][4].

OC1=C2C(OC(C3=CC(OC)=C(C=C3)O)=CC2=O)=CC(O)=C1C/C=C(C)/CC/C=C(C)\C

-20°C

12352200