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CAPG antibody [N3C3]

Name: CAPG antibody [N3C3]
SKU: GTX114301_G10
Availability: BackOrder

GTX114301

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetCAPG

Overview

Supplier
GeneTex
Product Name
CAPG antibody [N3C3]
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID822
Target name
CAPG
Target description
capping actin protein, gelsolin like
Target synonyms
AFCP, HEL-S-66, MCP, macrophage-capping protein, actin-regulatory protein CAP-G, capping protein (actin filament), gelsolin-like, epididymis secretory protein Li 66, gelsolin-like capping protein
Host
Rabbit
Isotype
IgG
Protein IDP40121
Protein Name
Macrophage-capping protein
Scientific Description
This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed, but have not been fully described. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Ohkawa Y, Kanto N, Nakano M, et al. Involvement of langerin in the protective function of a keratan sulfate-based disaccharide in an emphysema mouse model. J Biol Chem. 2023,299(8):105052. doi: 10.1016/j.jbc.2023.105052
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Wu Q, Tan Z, Xiong Y, et al. Comprehensive analysis of ferroptosis-related genes for clinical and biological significance in hepatocellular carcinoma. Discov Oncol. 2023,14(1):69. doi: 10.1007/s12672-023-00677-4
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Tsai TJ, Chao WY, Chen CC, et al. Gelsolin-like Actin-capping Protein (CapG) Overexpression in the Cytoplasm of Human Hepatocellular Carcinoma, Associated with Cellular Invasion, Migration and Tumor Prognosis. Anticancer Res. 2018,38(7):3943-3950. doi: 10.21873/anticanres.12680
Read this paper