Capillarisin [56365-38-9]

TargetMol Chemicals

Capillarisin [56365-38-9]

999

56365-38-9

Research Use Only

C16H12O7

316.26

Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cells, it inhibits cancer cell growth of osteosarcoma cells by inducing apoptosis accompanied with G0/G1-phase cell cycle arrest and loss in mitochondrial membrane potential.Capillarisin has anti-inflammatory activity, can inhibit LPS-induced inflammation by blocking TLR4-mediated NF-IB and MAPKs activation in BV2 microglia. Capillarisin possesses promising anti-hyperalgesic and anti-allodynic effects through the inhibition of various inflammatory pain signaling.

COc1c(O)cc2oc(Oc3ccc(O)cc3)cc(=O)c2c1O

-20°C

12352200