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Capivasertib (AZD5363)

M2303
AbMole BioScience
CAS Number1143532-39-1
DownloadDatasheet
Product group Chemicals
Estimated Purity>99%
Molecular Weight428.92
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    Capivasertib (AZD5363)
  • Delivery Days Customer
    9
  • CAS Number
    1143532-39-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Estimated Purity
    >99%
  • Molecular Formula
    C21H25ClN6O2
  • Molecular Weight
    428.92
  • Scientific Description
    Capivasertib (AZD5363) is a potentially first-in-class, orally effective pan-AKT inhibitor with strong inhibition against all three AKT isomers (AKT1/2/3) at an IC50 of 3 nM/8 nM/8 nM. It also showed similar inhibitory effect on P70S6K/PKA and low inhibitory activity on ROCK1/2.
  • SMILES
    NC1(CCN(CC1)C2=NC=NC3=C2C=C[NH]3)C(=O)NC(CCO)C4=CC=C(Cl)C=C4
  • UNSPSC
    12352200