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Capmatinib hydrochloride

Name: Capmatinib hydrochloride
SKU: ORB1089428_B48
Availability: BackOrder

ORB1089428

Molecular Weight503.3562458

Product group Chemicals

Overview

Supplier
Biorbyt
Product Name
Capmatinib hydrochloride
Delivery Days Customer
10
Certification
Research Use Only
Molecular Formula
C23H21CL2FN6O2
Molecular Weight
503.3562458
Scientific Description
Capmatinib, also known as INCB28060 and INC280, is an orally bioavailable inhibitor of the proto-oncogene c-Met with potential antineoplastic activity. c-Met inhibitor INC280 selectively binds to c-Met, thereby inhibiting c-Met phosphorylation and disrupting c-Met signal transduction pathways. This may induce cell death in tumor cells overexpressing c-Met protein or expressing constitutively activated c-Met protein. Capmatinib was approved in 2020.
SMILES
FC1=C(C(NC)=O)C=CC(=C1)C1C=NC2=NC=C(CC3C=CC4=C(C=CC=N4)C=3)N2N=1.Cl.Cl.O
UNSPSC
12352200