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Capmatinib

S2788
Selleck Chemicals
Estimated Purity...
Product group Chemicals
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    Capmatinib (INCB28060) [1029712-80-8]
  • Delivery Days Customer
    9
  • Certification
    Research Use Only
  • Estimated Purity
    ...
  • Scientific Description
    Capmatinib is a novel, ATP-competitive inhibitor of c-MET with IC50 of 0.13 nM in a cell-free assay, inactive against RONbeta, as well as EGFR and HER-3. Capmatinib (INCB28060) inhibits Wnt/beta-catenin and EMT signaling pathways and induces apoptosis in diffuse gastric cancer positive for c-MET amplification. Phase 1.
  • Storage Instruction
    -80°C
  • UNSPSC
    51202000

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