
IHC image of CSB-PA740238OA01HU diluted at 1:100 and staining in paraffin-embedded human pancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
CAPRIN2 Antibody
CSB-PA740238OA01HU
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCAPRIN2
Overview
- SupplierCusabio
- Product NameCAPRIN2 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID65981
- Target nameCAPRIN2
- Target descriptioncaprin family member 2
- Target synonymsC1q domain-containing protein 1; C1QDC1; caprin-2; cytoplasmic activation/proliferation-associated protein 2; EEG1; EEG-1; gastric cancer multidrug resistance-associated protein; RNA granule protein 140; RNG140
- HostRabbit
- IsotypeIgG
- Protein IDQ6IMN6
- Protein NameCaprin-2
- Scientific DescriptionPromotes phosphorylation of the Wnt coreceptor LRP6, leading to increased activity of the canonical Wnt signaling pathway (PubMed:18762581). Faciliates constitutive LRP6 phosphorylation by CDK14/CCNY during G2/M stage of the cell cycle, which may potentiate cells for Wnt signaling (PubMed:27821587). May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins involved in synaptic plasticity in neurons (By similarity). Involved in regulation of growth as erythroblasts shift from a highly proliferative state towards their terminal phase of differentiation (PubMed:14593112). May be involved in apoptosis (PubMed:14593112).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161