Capsaicin from Capsicum annuum [404-86-4]

Chemodex

Capsaicin from Capsicum annuum [404-86-4]

10

6.1

404-86-4

Research Use Only

>95%

Danger,Excepted quantity

C18H27NO3

305.41

Chemical. CAS: 404-86-4. Formula: C18H27NO3. MW: 305.41. Synthetic. Primary active component of the heat and pain-eliciting lipid-soluble fraction of Capsicum pepper. Acts as an agonist at the vanilloid receptor (VR1; TRPV1) receptor, a ligand-gated non-selective cation channel. Capsaicin elicits a sensation of burning pain by activation of TRPV1 on small, non-myelinated polymodal C-type nociceptive nerve fibers. It has been shown to have antinociceptive, anti-inflammatory, anti-obesity, neuroprotective and anticancer effects. - Primary active component of the heat and pain-eliciting lipid-soluble fraction of Capsicum pepper. Acts as an agonist at the vanilloid receptor (VR1; TRPV1) receptor, a ligand-gated non-selective cation channel. Capsaicin elicits a sensation of burning pain by activation of TRPV1 on small, non-myelinated polymodal C-type nociceptive nerve fibers. It has been shown to have antinociceptive, anti-inflammatory, anti-obesity, neuroprotective and anticancer effects.

COC1=C(O)C=CC(CNC(=O)CCCC\C=C\C(C)C)=C1

2°C to 8°C,RT

UN 2811

12352200