Carbonic anhydrase inhibitor 14 [2410402-75-2]

MedChem Express

Carbonic anhydrase inhibitor 14 [2410402-75-2]

10

2410402-75-2

Research Use Only

C18H17N7O2S

395.44

Carbonic anhydrase inhibitor 14 (Compound 8b) is a carbonic anhydrase (CA) inhibitor with Ki values of 1203, 99.7, 9.4 and 27.7 nM against hCA I, hCA II, hCA IX and hCA XII, respectively. Carbonic anhydrase inhibitor 14 can also inhibit CDK2 with an IC50 of 20.3 microM. Carbonic anhydrase inhibitor 14 shows antitumor activity[1].

O=S(C1=CC=C(/N=N/C2=C(NC(C3=CC=C(C)C=C3)=C4)N4N=C2N)C=C1)(N)=O

12131703