CARD11 antibody, C-term

GeneTex

CARD11 antibody, C-term

7

WB: 1-3microg/ml. IHC-P: 2-5microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.50 mg/ml

Unconjugated

CARD11

caspase recruitment domain family member 11

bcl10-interacting maguk protein 3; BENTA; BIMP3; CARD-containing MAGUK protein 1; carma 1; CARMA1; caspase recruitment domain-containing protein 11; IMD11; IMD11A; PPBL

Goat

IgG

Caspase recruitment domain-containing protein 11

The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10. [provided by RefSeq, Jul 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203