CARD11 Antibody

Aviva Systems Biology

CARD11 Antibody

23

WB: 1:500 - 1:2,000. IHC: 1:50 - 1:200. IF: 1:50 - 1:100

ImmunoFluorescence, Western Blot, ImmunoHistoChemistry

Research Use Only

Polyclonal

Unconjugated

Liquid

CARD11

caspase recruitment domain family member 11

BENTA, BIMP3, CARMA1, IMD11, IMD11A, PPBL, caspase recruitment domain-containing protein 11, CARD-containing MAGUK protein 1, bcl10-interacting maguk protein 3, carma 1

Rabbit

IgG

Caspase recruitment domain-containing protein 11

The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.

Human, Mouse

-20°C

41116161