Immunofluorescence staining of Hela cells with CSB-PA682727LA01HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
Immunofluorescence staining of Hela cells with CSB-PA682727LA01HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
CARD16 Antibody
CSB-PA682727LA01HU
ApplicationsImmunoFluorescence, ELISA
Product group Antibodies
ReactivityHuman
TargetCARD16
Overview
- SupplierCusabio
- Product NameCARD16 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID114769
- Target nameCARD16
- Target descriptioncaspase recruitment domain family member 16
- Target synonymsCOP, COP1, LLID-114769, PSEUDO-ICE, caspase recruitment domain-containing protein 16, CARD only domain-containing protein 1, CARD only protein, CARD-only protein 1, caspase recruitment domain-only protein 1, caspase-1 dominant-negative inhibitor pseudo-ICE, caspase-1 inhibitor COP, pseudo interleukin-1 beta converting enzyme, pseudo interleukin-1beta converting enzyme, pseudo-IL1B-converting enzyme
- HostRabbit
- IsotypeIgG
- Protein IDQ5EG05
- Protein NameCaspase recruitment domain-containing protein 16
- Scientific DescriptionCaspase inhibitor. Acts as a regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro-inflammatory cytokine response. Also able to inhibit CASP1-mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC41116161
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