Cardiac Troponin C antibody

GeneTex

Cardiac Troponin C antibody

9

WB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

Unconjugated

TNNC1

troponin C1, slow skeletal and cardiac type

CMD1Z, CMH13, TN-C, TNC, TNNC, troponin C, slow skeletal and cardiac muscles, cardiac troponin C, slow twitch skeletal/cardiac muscle troponin C, troponin C type 1 (slow)

Rabbit

IgG

Troponin C, slow skeletal and cardiac muscles

Troponin is a central regulatory protein of striated muscle contraction, and together with tropomyosin, is located on the actin filament. Troponin consists of 3 subunits: TnI, which is the inhibitor of actomyosin ATPase; TnT, which contains the binding site for tropomyosin; and TnC, the protein encoded by this gene. The binding of calcium to TnC abolishes the inhibitory action of TnI, thus allowing the interaction of actin with myosin, the hydrolysis of ATP, and the generation of tension. Mutations in this gene are associated with cardiomyopathy dilated type 1Z. [provided by RefSeq, Oct 2008]

-20°C or -80°C,2°C to 8°C

12352203