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Cardiac Troponin T antibody [1C11]

Cardiac Troponin T antibody [1C11]

GTX28295
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, Other Application, Purification/Extraction/Isolation
Product group Antibodies
TargetTNNT2
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Overview

  • Supplier
    GeneTex
  • Product Name
    Cardiac Troponin T antibody [1C11]
  • Delivery Days Customer
    9
  • Application Supplier Note
    *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, Other Application, Purification/Extraction/Isolation
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    1C11
  • Conjugate
    Unconjugated
  • Gene ID7139
  • Target name
    TNNT2
  • Target description
    troponin T2, cardiac type
  • Target synonyms
    CMD1D, CMH2, CMPD2, LVNC6, RCM3, TnTC, cTnT, troponin T, cardiac muscle, cardiomyopathy, dilated 1D (autosomal dominant), cardiomyopathy, hypertrophic 2, troponin T type 2 (cardiac)
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP45379
  • Protein Name
    Troponin T, cardiac muscle
  • Scientific Description
    The protein encoded by this gene is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with dilated cardiomyopathy. Transcripts for this gene undergo alternative splicing that results in many tissue-specific isoforms, however, the full-length nature of some of these variants has not yet been determined. [provided by RefSeq, Jul 2008]
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352203

References

  • Saito Y, Nose N, Iida T, et al. In vivo tracking transplanted cardiomyocytes derived from human induced pluripotent stem cells using nuclear medicine imaging. Front Cardiovasc Med. 2023,10:1261330. doi: 10.3389/fcvm.2023.1261330
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  • Saito Y, Nakamura K, Yoshida M, et al. Enhancement of pacing function by HCN4 overexpression in human pluripotent stem cell-derived cardiomyocytes. Stem Cell Res Ther. 2022,13(1):141. doi: 10.1186/s13287-022-02818-y
    Read this paper
  • Xu Y, Rothe R, Voigt D, et al. Convergent synthesis of diversified reversible network leads to liquid metal-containing conductive hydrogel adhesives. Nat Commun. 2021,12(1):2407. doi: 10.1038/s41467-021-22675-2
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  • Hoffman RM, Amoh Y. Beating Heart Cells from Hair-Follicle-Associated Pluripotent (HAP) Stem Cells. Methods Mol Biol. 2018,1842:241-254. doi: 10.1007/978-1-4939-8697-2_18
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  • Hoffman RM. Human Hair Follicle Associated-Pluripotent (hHAP) Stem Cells Differentiate to Cardiac Muscle Cells. Methods Mol Biol. 2019,1879:385-392. doi: 10.1007/7651_2018_170
    Read this paper
  • Williams AL, Khadka V, Tang M, et al. HIF1 mediates a switch in pyruvate kinase isoforms after myocardial infarction. Physiol Genomics. 2018,50(7):479-494. doi: 10.1152/physiolgenomics.00130.2017
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  • Lao S, Xu J, Liu Y, et al. A comparative study of the influence of two types of PHEMA stents on the differentiation of ASCs to myocardial cells. Mol Med Rep. 2017,16(1):507-514. doi: 10.3892/mmr.2017.6680
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  • Shirai K, Hamada Y, Arakawa N, et al. Hypoxia Enhances Differentiation of Hair Follicle-Associated-Pluripotent (HAP) Stem Cells to Cardiac-Muscle Cells. J Cell Biochem. 2017,118(3):554-558. doi: 10.1002/jcb.25734
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  • Yashiro M, Mii S, Aki R, et al. Protocols for Efficient Differentiation of Hair Follicle-Associated Pluripotent (HAP) Stem Cells to Beating Cardiac Muscle Cells. Methods Mol Biol. 2016,1453:151-9. doi: 10.1007/978-1-4939-3786-8_16
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  • Yamazaki A, Hamada Y, Arakawa N, et al. Early-age-dependent selective decrease of differentiation potential of hair-follicle-associated pluripotent (HAP) stem cells to beating cardiac-muscle cells. Cell Cycle. 2016,15(19):2619-2625.
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