CASP12 (N) Antibody, Rabbit Polyclonal

Biorbyt

CASP12 antibody

16

WB:1:500-1:1000 WB

CASP12

caspase 12 (gene/pseudogene)

CASP-12; CASP12P1; caspase 12 pseudogene 1; inactive caspase-12

Inactive caspase-12

Rabbit polyclonal to CASP12.Inactive caspase-12 (CASP12) belongs to the peptidase C14A family and has no protease activity. Itmay reduce cytokine release in response to bacterial lipopolysaccharide during infections. It alsoreduces activation of NF-kappa-B in response to TNF. The variant Arg-125 (Csp12-L) of CASP12 mayincrease the susceptibility to sever sepsis, and may also increase the mortality rate in sepsis patients.

-20°C

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