Western blot analysis of extracts of various cell lines using Caspase-14 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using Caspase-14 Polyclonal Antibody at 1:1000 dilution.
CASP14 Polyclonal Antibody
E-AB-61201
Product group Antibodies
Overview
- SupplierElabscience
- Product NameCASP14 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThis gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.
- UNSPSC12352203