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ProductsBack/Caspase 9 antibody [N2C3]

Caspase 9 antibody [N2C3]

GTX112888
GeneTex
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
DownloadDatasheet
Product group Antibodies
ReactivityCanine, Human, Mouse, Rat
TargetCASP9
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Overview

  • Supplier
    GeneTex
  • Product Name
    Caspase 9 antibody [N2C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.55 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID842
  • Target name
    CASP9
  • Target description
    caspase 9
  • Target synonyms
    APAF3; APAF-3; apoptotic protease activating factor 3; apoptotic protease MCH-6; caspase 9, apoptosis-related cysteine peptidase; caspase-9; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; PPP1R56; protein phosphatase 1, regulatory subunit 56
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP55211
  • Protein Name
    Caspase-9
  • Scientific Description
    This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspase APAF1; this step is thought to be one of the earliest in the caspase activation cascade. Alternative splicing results in two transcript variants which encode different isoforms. [provided by RefSeq]
  • Reactivity
    Canine, Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Hypoxia-Induced Kidney Injury in Newborn Rats.
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  • Ameliorative effects of Schisandrin B on Schistosoma mansoni-induced hepatic fibrosis in vivo. Lam HYP et al., 2021 Jun, PLoS Negl Trop Dis
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  • Melatonin Downregulates PD-L1 Expression and Modulates Tumor Immunity in KRAS-Mutant Non-Small Cell Lung Cancer. Chao YC et al., 2021 May 26, Int J Mol Sci
    Read more
  • Mitochondrial dynamics in Angiostrongylus cantonensis-infected mouse brain. Lam HYP et al., 2021 Feb, Parasitol Int
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  • Albendazole-Schisandrin B Co-Therapy on Angiostrongylus cantonensis-Induced Meningoencephalitis in Mice. Lam HYP et al., 2020 Jul 5, Biomolecules
    Read more
  • Djulis (Chenopodium Formosanum) Prevents Colon Carcinogenesis via Regulating Antioxidative and Apoptotic Pathways in Rats. Lee CW et al., 2019 Sep 10, Nutrients
    Read more
  • Cloning, expression, and purification of the recombinant pro-apoptotic dominant-negative survivin T34A-C84A protein in Escherichia coli. Tsai SL et al., 2019 Aug, Protein Expr Purif
    Read more
  • Metformin triggers the intrinsic apoptotic response in human AGS gastric adenocarcinoma cells by activating AMPK and suppressing mTOR/AKT signaling. Lu CC et al., 2019 Apr, Int J Oncol
    Read more
  • Artocarpin induces cell apoptosis in human osteosarcoma cells through endoplasmic reticulum stress and reactive oxygen species. Lee CW et al., 2019 Aug, J Cell Physiol
    Read more
  • Benzyl isothiocyanate (BITC) triggers mitochondria-mediated apoptotic machinery in human cisplatin-resistant oral cancer CAR cells. Lee CF et al., 2018 Sep, Biomedicine (Taipei)
    Read more