Caspase 9 peptide

GeneTex

Caspase 9 peptide

9

The peptide is used for blocking the activity of anti-caspase-9 (GTX22013).Incubating the peptide with equal volume of antibody for 30 min at 37C usually completely blocksthe antibody activity in Western blotting.

Neutralisation/Blocking

Research Use Only

0.20 mg/ml

Unconjugated

CASP9

caspase 9

APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56, caspase-9, ICE-like apoptotic protease 6, apoptotic protease MCH-6, apoptotic protease activating factor 3, caspase 9, apoptosis-related cysteine peptidase, protein phosphatase 1, regulatory subunit 56

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase-8 and Caspase-9. Activated initiator caspases then process effector caspases, such as Caspase-3 and Caspase-7, which in turn cause cell collapse.

-20°C

41116100

Human