Western Blot Positive WB detected in: HL60 whole cell lysate, SH-SY5Y whole cell lysate, Jurkat whole cell lysate, Hela whole cell lysate All lanes: CASTOR2 antibody at 1:2000 Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 37 kDa Observed band size: 37 kDa

CASTOR2 Antibody

Name: CASTOR2 Antibody
SKU: CSB-PA28239A0RB_C90
Availability: BackOrder

CSB-PA28239A0RB

ApplicationsWestern Blot, ELISA

Product group Antibodies

ReactivityHuman

TargetCASTOR2

Overview

Supplier
Cusabio
Product Name
CASTOR2 Antibody
Delivery Days Customer
20
Applications
Western Blot, ELISA
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID729438
Target name
CASTOR2
Target description
cytosolic arginine sensor for mTORC1 subunit 2
Target synonyms
cellular arginine sensor for mTORC1 protein 2; cytosolic arginine sensor for mTORC1 subunit 1; cytosolic arginine sensor for mTORC1 subunit 2; GATS protein like 2; GATS protein-like 1; GATSL1; GATSL2; GATS-like protein 1; GATS-like protein 2
Host
Rabbit
Isotype
IgG
Protein IDA6NHX0
Protein Name
Cytosolic arginine sensor for mTORC1 subunit 2
Scientific Description
Functions as a negative regulator of the TORC1 signaling pathway through the GATOR complex. As part of homodimers or heterodimers with CASTOR1, directly binds and inhibits the GATOR subcomplex GATOR2 and thereby mTORC1. Does not directly bind arginine, but binding of arginine to CASTOR1 disrupts the interaction of CASTOR2-containing heterodimers with GATOR2 which can in turn activate mTORC1 and the TORC1 signaling pathway.
Reactivity
Human
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

CASTOR2 Antibody

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Overview

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