Bio-Connect

Catalase antibody

GTX110704
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCAT
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Overview

  • Supplier
    GeneTex
  • Product Name
    Catalase antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.47 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID847
  • Target name
    CAT
  • Target description
    catalase
  • Target synonyms
    catalase; epididymis secretory sperm binding protein
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP04040
  • Protein Name
    Catalase
  • Scientific Description
    This gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimers disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Hepatocyte integrity depends on c-Jun-controlled proliferation in Schistosoma mansoni infected mice.
    Read more
  • Fenofibrate attenuates the cytotoxic effect of cisplatin on lung cancer cells by enhancing the antioxidant defense system in vitro.
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  • Effects of aging and long-term physical activity on mitochondrial physiology and redox state of the cortex and cerebellum of female rats.
    Read more
  • Liraglutide Attenuates Glucolipotoxicity-Induced RSC96 Schwann Cells Inflammation and Dysfunction.
    Read more
  • Molecular and Cellular Response of the Myocardium (H9C2 Cells) Towards Hypoxia and HIF-1alpha Inhibition. Osuru HP et al., 2022, Front Cardiovasc Med
    Read more
  • Antioxidant Effects of DPP-4 Inhibitors in Early Stages of Experimental Diabetic Retinopathy. Ramos H et al., 2022 Jul 21, Antioxidants (Basel)
    Read more
  • Cytoprotective effects of a tripeptide from Chinese Baijiu against AAPH-induced oxidative stress in HepG2 cells via Nrf2 signaling. Wu J et al., 2018 Mar 16, RSC Adv
    Read more
  • Chemotherapy impairs skeletal muscle mitochondrial homeostasis in early breast cancer patients. Mallard J et al., 2022 Jun, J Cachexia Sarcopenia Muscle
    Read more
  • Skeletal myopathy in a rat model of postmenopausal heart failure with preserved ejection fraction.
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  • Salvianolic Acid C Protects against Cisplatin-Induced Acute Kidney Injury through Attenuation of Inflammation, Oxidative Stress and Apoptotic Effects and Activation of the CaMKK-AMPK-Sirt1-Associated Signaling Pathway in Mouse Models. Chien LH et al., 2021 Oct 15, Antioxidants (Basel)
    Read more