Catalase antibody
GTX110704
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetCAT
Overview
- SupplierGeneTex
- Product NameCatalase antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.47 mg/ml
- ConjugateUnconjugated
- Gene ID847
- Target nameCAT
- Target descriptioncatalase
- Target synonymscatalase, epididymis secretory sperm binding protein
- HostRabbit
- IsotypeIgG
- Protein IDP04040
- Protein NameCatalase
- Scientific DescriptionThis gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimers disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Härle L, von Bülow V, Knedla L, et al. Hepatocyte integrity depends on c-Jun-controlled proliferation in Schistosoma mansoni infected mice. Sci Rep. 2023,13(1):20390. doi: 10.1038/s41598-023-47646-zRead this paper
- Kogami M, Abe S, Nakamura H, et al. Fenofibrate attenuates the cytotoxic effect of cisplatin on lung cancer cells by enhancing the antioxidant defense system in vitro. Oncol Lett. 2023,26(1):313. doi: 10.3892/ol.2023.13899Read this paper
- Mesquita PHC, Osburn SC, Godwin JS, et al. Effects of aging and long-term physical activity on mitochondrial physiology and redox state of the cortex and cerebellum of female rats. Physiol Rep. 2022,10(24):e15542. doi: 10.14814/phy2.15542Read this paper
- Kornelius E, Tsou SH, Chang CC, et al. Liraglutide Attenuates Glucolipotoxicity-Induced RSC96 Schwann Cells' Inflammation and Dysfunction. Biomolecules. 2022,12(10). doi: 10.3390/biom12101338Read this paper
- Osuru HP, Lavallee M, Thiele RH. Molecular and Cellular Response of the Myocardium (H9C2 Cells) Towards Hypoxia and HIF-1α Inhibition. Front Cardiovasc Med. 2022,9:711421. doi: 10.3389/fcvm.2022.711421Read this paper
- Ramos H, Bogdanov P, Huerta J, et al. Antioxidant Effects of DPP-4 Inhibitors in Early Stages of Experimental Diabetic Retinopathy. Antioxidants (Basel). 2022,11(7). doi: 10.3390/antiox11071418Read this paper
- Wu J, Sun B, Luo X, et al. Cytoprotective effects of a tripeptide from Chinese Baijiu against AAPH-induced oxidative stress in HepG2 cells via Nrf2 signaling. RSC Adv. 2018,8(20):10898-10906. doi: 10.1039/c8ra01162aRead this paper
- Mallard J, Hucteau E, Charles AL, et al. Chemotherapy impairs skeletal muscle mitochondrial homeostasis in early breast cancer patients. J Cachexia Sarcopenia Muscle. 2022,13(3):1896-1907. doi: 10.1002/jcsm.12991Read this paper
- Kelley RC, Betancourt L, Noriega AM, et al. Skeletal myopathy in a rat model of postmenopausal heart failure with preserved ejection fraction. J Appl Physiol (1985). 2022,132(1):106-125. doi: 10.1152/japplphysiol.00170.2021Read this paper
- Chien LH, Wu CT, Deng JS, et al. Salvianolic Acid C Protects against Cisplatin-Induced Acute Kidney Injury through Attenuation of Inflammation, Oxidative Stress and Apoptotic Effects and Activation of the CaMKK-AMPK-Sirt1-Associated Signaling Pathway in Mouse Models. Antioxidants (Basel). 2021,10(10). doi: 10.3390/antiox10101620Read this paper
Datasheet
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