Catalase antibody
GTX110704
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetCAT
Overview
- SupplierGeneTex
- Product NameCatalase antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.47 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID847
- Target nameCAT
- Target descriptioncatalase
- Target synonymscatalase; epididymis secretory sperm binding protein
- HostRabbit
- IsotypeIgG
- Protein IDP04040
- Protein NameCatalase
- Scientific DescriptionThis gene encodes catalase, a key antioxidant enzyme in the bodies defense against oxidative stress. Catalase is a heme enzyme that is present in the peroxisome of nearly all aerobic cells. Catalase converts the reactive oxygen species hydrogen peroxide to water and oxygen and thereby mitigates the toxic effects of hydrogen peroxide. Oxidative stress is hypothesized to play a role in the development of many chronic or late-onset diseases such as diabetes, asthma, Alzheimers disease, systemic lupus erythematosus, rheumatoid arthritis, and cancers. Polymorphisms in this gene have been associated with decreases in catalase activity but, to date, acatalasemia is the only disease known to be caused by this gene. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Molecular and Cellular Response of the Myocardium (H9C2 Cells) Towards Hypoxia and HIF-1alpha Inhibition. Osuru HP et al., 2022, Front Cardiovasc MedRead more
- Antioxidant Effects of DPP-4 Inhibitors in Early Stages of Experimental Diabetic Retinopathy. Ramos H et al., 2022 Jul 21, Antioxidants (Basel)Read more
- Cytoprotective effects of a tripeptide from Chinese Baijiu against AAPH-induced oxidative stress in HepG2 cells via Nrf2 signaling. Wu J et al., 2018 Mar 16, RSC AdvRead more
- Chemotherapy impairs skeletal muscle mitochondrial homeostasis in early breast cancer patients. Mallard J et al., 2022 Jun, J Cachexia Sarcopenia MuscleRead more
- Salvianolic Acid C Protects against Cisplatin-Induced Acute Kidney Injury through Attenuation of Inflammation, Oxidative Stress and Apoptotic Effects and Activation of the CaMKK-AMPK-Sirt1-Associated Signaling Pathway in Mouse Models. Chien LH et al., 2021 Oct 15, Antioxidants (Basel)Read more
- Peroxisome proliferator-activated receptor delta rescues xCT-deficient cells from ferroptosis by targeting peroxisomes. Hwang JS et al., 2021 Nov, Biomed PharmacotherRead more
- Protective effects of mycosporine-like amino acid-containing emulsions on UV-treated mouse ear tissue from the viewpoints of antioxidation and antiglycation. Waditee-Sirisattha R et al., 2021 Oct, J Photochem Photobiol BRead more
- Catalase Mediates the Inhibitory Actions of PPARdelta against Angiotensin II-Triggered Hypertrophy in H9c2 Cardiomyocytes. Hwang JS et al., 2021 Jul 29, Antioxidants (Basel)Read more
- Sanghuangporus sanghuang Mycelium Prevents Paracetamol-Induced Hepatotoxicity through Regulating the MAPK/NF-kappaB, Keap1/Nrf2/HO-1, TLR4/PI3K/Akt, and CaMKKbeta/LKB1/AMPK Pathways and Suppressing Oxidative Stress and Inflammation. Jiang WP et al., 2021 Jun 2, Antioxidants (Basel)Read more
- Melatonin Successfully Rescues the Hippocampal Molecular Machinery and Enhances Anti-oxidative Activity Following Early-Life Sleep Deprivation Injury. Chang HM et al., 2021 May 13, Antioxidants (Basel)Read more